PUBLICATIONS

Understanding the pain experience of lionfish envenomation.Mouchbahani-Constance S, Choinière M, Sharif-Naeini R. Pain Rep. 2023 Aug 3;8(5):e1090. doi: 10.1097/PR9.0000000000001090.

Modulation of SK Channels via Calcium Buffering Tunes Intrinsic Excitability of Parvalbumin Interneurons in Neuropathic Pain: A Computational and Experimental Investigation. Ma X, Miraucourt LS, Qiu H, Sharif-Naeini R, Khadra A.J Neurosci. 2023 Aug 2;43(31):5608-5622. doi: 10.1523/JNEUROSCI.0426-23.2023.

Preclinical orofacial pain assays and measures and chronic primary orofacial pain research: where we are and where we need to go. Sadighparvar S, Al-Hamed FS, Sharif-Naeini R, Meloto CB. Front Pain Res (Lausanne). 2023 May 24;4:1150749. doi: 10.3389/fpain.2023.1150749

Modulating the activity of human nociceptors with a SCN10A promoter-specific viral vector tool. Mouchbahani-Constance S, Lagard C, Schweizer J, Labonté I, Georgiopoulos M, Otis C, St-Louis M, Troncy E, Sarret P, Ribeiro-Da-Silva A, Ouellet JA, Séguéla P, Paquet ME, Sharif-Naeini R. Neurobiol Pain. 2023 Jan 30;13:100120. doi: 10.1016/j.ynpai.2023.100120.

Multiscale structural anisotropy steers plant organ actuation. Sleboda DA, Geitmann A, Sharif-Naeini R. Curr Biol. 2023 Feb 27;33(4):639-646.e3. doi: 10.1016/j.cub.2022.12.013

Spinal processing of cold information by Kcnip2 neurons. Qiu H, Miraucourt L, Sharif-Naeini R. Neuron. 2023 Jan 4;111(1):8-9. doi: 10.1016/j.neuron.2022.12.018

Mechanosensitive ion channels contribute to mechanically evoked rapid leaflet movement in Mimosa pudica.Tran D, Petitjean H, Chebli Y, Geitmann A, Sharif-Naeini R. Plant Physiol. 2021 Nov 3;187(3):1704-1712. doi: 10.1093/plphys/kiab333

Proteomic and Transcriptomic Techniques to Decipher the Molecular Evolution of Venoms. Mouchbahani-Constance S, Sharif-Naeini N. 2021 February; 13(2), 154. doi: https://doi.org/10.3390/toxins13020154

Loss of SLC9A6/NHE6 impairs nociception in a mouse model of Christianson syndrome. Petitjean H*, Fatima T*, Mouchbahani-Constance S, Davidova A, Ferland C, Orlowski J, Sharif-Naeini R. 2020 November;161:2619-2628. doi: 10.1097/j.pain.0000000000001961

TACAN is an ion channel involved in sensing mechanical pain. Beaulieu-Laroche L*, Christin M, Donoghue A, Agosti F, Yousefpour N, Petitjean H, Davidova A, Stanton C, Khan U, Dietz C, Faure E, Fatima T, MacPherson A, Mouchbahani-Constance S, Bisson DG, Haglund L, Ouellet JA, Stone LS, Samson J, Smith MJ, Ask K, Ribeiro-da-Silva A, Blunck R, Poole K, Bourinet E, Sharif-Naeini R. Cell. 2020 March 5; 180:1-12. doi: 10.1016/j.cell.2020.01.033

Bursting Enables GRP Neurons to Engage Spinal Itch Circuits. Petitjean H, Séguéla P, Sharif-Naeini R. Neuron. 2019 Jul 3;103(1):5-7. doi: 10.1016/j.neuron.2019.06.009.

Recruitment of Spinoparabrachial Neurons by Dorsal Horn Calretinin Neurons. Petitjean H, B Bourojeni F, Tsao D, Davidova A, Sotocinal SG, Mogil JS, Kania A, Sharif-Naeini R. Cell Rep. 2019 Aug 6;28(6):1429-1438.e4. doi: 10.1016/j.celrep.2019.07.048.

Lionfish venom elicits pain predominantly through the activation of nonpeptidergic nociceptors. Mouchbahani-Constance S, Lesperance LS, Petitjean H, Davidova A, Macpherson A, Prescott SA, Sharif-Naeini R. Pain. 2018 Nov;159(11):2255-2266. doi: 10.1097/j.pain.0000000000001326.

Dynamic regulation of TREK1 gating by Polycystin 2 via a Filamin A-mediated cytoskeletal Mechanism. Li Fraine S, Patel A, Duprat F, Sharif-Naeini R. Sci Rep. 2017 Dec 12;7(1):17403. doi: 10.1038/s41598-017-16540-w.

A mechanosensitive Ca2+ channel activity is dependent on the developmental regulator DEK1. Tran D, Galletti R, Neumann ED, Dubois A, Sharif-Naeini R, Geitmann A, Franchisse JM, Hamant O, Ingram GC. Nat Commun. 201 Oct 18;8(1):1009. doi: 10.1038/s41467-017-00878-w.

Mechanosensitive ion channels in articular nociceptors drive mechanical allodynia in osteoarthritis. He BH, Christin M, Mouchbahani-Constance S, Davidova A, Sharif-Naeini R. Osteoarthritis & Cartilage. 2017 Dec;25(12):2091-2099. doi: 10.1016/j.joca.2017.08.012. Epub 2017 Sep 5.

A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins. François A, Low SA, Sypek EI, Christensen AJ, Sotoudeh C, Beier KT, Ramakrishnan C, Ritola KD, Sharif-Naeini R, Deisseroth K, Delp SL, Malenka RC, Luo L, Hantman AW, Scherrer G. Neuron. 2017 Feb 22;93(4):822-839.e6. doi: 10.1016/j.neuron.2017.01.008. Epub 2017 Feb 2.

eIF2alpha phosphorylation controls thermal nociception. Khoutorsky A, Sorge RE, Prager-Khoutorsky M, Pawlowski SA, Longo G, Jafarnejad SM, Tahmasebi S, Martin LJ, Pitcher MH, Gkogkas CG, Sharif-Naeini R, Ribeiro-da-Silva A, Bourque CW, Cervero F, Mogil JS, Sonenberg N. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11949-11954. Epub 2016 Oct 3.

Differential Regulation of 6- and 7- Transmembrane Helix Variants of mu-Opioid Receptor in Response to Morphine Stimulation. Convertino M, Samoshkin A, Viet CT, Gauthier J, Li Fraine SP, Sharif-Naeini R, Schmidt BL, Maixner W, Diatchenko L, Dokholyan NV. PLoS One. 2015 Nov 10;10(11):e0142826. doi: 10.1371/journal.pone.0142826. eCollection 2015.

Dorsal Horn Parvalbumin Neurons are Gate-Keepers of Touch-Evoked Pain after Nerve Injury. Petitjean H, Pawlowski SA, Fraine SL, Sharif B, Hamad D, Fatima T, Berg J, Brown CM, Jan LY, Ribeiro-da-Silva A, Braz JM, Basbaum AI, Sharif-Naeini R. Cell Rep. 2015 Nov 10;13(6):1246-1257. doi: 10.1016/j.celrep.2015.09.080. Epub 2015 Oct 29.

Contribution of mechanosensitive ion channels to somatosensation. Sharif-Naeini R. Prog Mol Biol Transl Sci. 2015;131:53-71. doi: 10.1016/bs.pmbts.2014.11.011. Epub 2015 Feb 10. Review.

Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein and antibody concerns. Solorzano C, Villafuerte D, Meda K, Cevikbas F, Bráz J, Sharif-Naeini R, Juarez-Salinas D, Llewellyn-Smith IJ, Guan Z, Basbaum AI. J Neurosci. 2015 Jan 14;35(2):648-57. doi: 10.1523/JNEUROSCI.2955-14.2015.

Selective involvement of serum response factor in pressure-induced myogenic tone in resistance arteries. Retailleau K, Toutain B, Galmiche G, Fassot C, Sharif-Naeini R, Kauffenstein G, Mericskay M, Duprat F, Grimaud L, Merot J, Lardeux A, Pizard A, Baudrie V, Jeunemaitre X, Feil R, Göthert JR, Lacolley P, Henrion D, Li Z, Loufrani L. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):339-46. doi: 10.1161/ATVBAHA.112.300708. Epub 2012 Dec 20.

 Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels. Peyronnet R, Sharif-Naeini R, Folgering JH, Arhatte M, Jodar M, El Boustany C, Gallian C, Tauc M, Duranton C, Rubera I, Lesage F, Pei Y, Peters DJ, Somlo S, Sachs F, Patel A, Honoré E, Duprat F. Cell Rep. 2012 Mar 29;1(3):241-50. doi: 10.1016/j.celrep.2012.01.006. Epub 2012 Mar 8.

Forebrain GABAergic neuron precursors integrate into adult spinal cord and reduce injury-induced neuropathic pain. Bráz JM, Sharif-Naeini R, Vogt D, Kriegstein A, Alvarez-Buylla A, Rubenstein JL, Basbaum AI. Neuron. 2012 May 24;74(4):663-75. doi: 10.1016/j.neuron.2012.02.033.

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Bohlen CJ, Chesler AT, Sharif-Naeini R, Medzihradszky KF, Zhou S, King D, Sánchez EE, Burlingame AL, Basbaum AI, Julius D. Nature. 2011 Nov 16;479(7373):410-4. doi: 10.1038/nature10607.

Targeting pain where it resides… In the brain. Sharif-Naeini R, Basbaum AI. Sci Transl Med. 2011 Jan 12;3(65):65ps1. doi: 10.1126/scitranslmed.3002077.

Osmotic and thermal control of magnocellular neurosecretory neurons — role of an N-terminal variant of Trpv1. Sudbury JR, Ciura S, Sharif-Naeini R, Bourque CW. Eur J Neurosci. 2010 Dec;32(12):2022-30. doi: 10.1111/j.1460-9568.2010.07512.x. Review.

Canonical TRP channels and mechanotransduction: from physiology to disease states. Patel A, Sharif-Naeini R, Folgering JR, Bichet D, Duprat F, Honoré E. Pflugers Arch. 2010 Aug;460(3):571-81. doi: 10.1007/s00424-010-0847-8. Epub 2010 May 21. Review.

Polycystin-1 and -2 dosage regulates pressure sensing. Sharif-Naeini R, Folgering JH, Bichet D, Duprat F, Lauritzen I, Arhatte M, Jodar M, Dedman A, Chatelain FC, Schulte U, Retailleau K, Loufrani L, Patel A, Sachs F, Delmas P, Peters DJ, Honoré E. Cell. 2009 Oct 30;139(3):587-96. doi: 10.1016/j.cell.2009.08.045.

Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels. Sharif-Naeini R, Folgering JH, Bichet D, Duprat F, Delmas P, Patel A, Honoré E. J Mol Cell Cardiol. 2010 Jan;48(1):83-9. doi: 10.1016/j.yjmcc.2009.03.020. Epub 2009 Apr 1. Review.

Neurophysiology of supraoptic neurons in C57/Bl mice studied in three acute in vitro preparations. Sharif-Naeini R, Ciura S, Stachniak TJ, Trudel E, Bourque CW.Prog Brain Res. 2008;170:229-42. doi: 10.1016/S0079-6123(08)00420-2.

Trpv1 gene required for thermosensory transduction and anticipatory secretion from vasopressin neurons during hyperthermia. Sharif-Naeini R, Ciura S, Bourque CW. Neuron. 2008 Apr 24;58(2):179-85. doi: 10.1016/j.neuron.2008.02.013.

The mechano-gated K(2P) channel TREK-1. Dedman A, Sharif-Naeini R, Folgering JH, Duprat F, Patel A, Honoré E. Eur Biophys J. 2009 Mar;38(3):293-303. doi: 10.1007/s00249-008-0318-8. Epub 2008 Mar 28. Review.

Molecular basis of the mammalian pressure-sensitive ion channels: focus on vascular mechanotransduction. Folgering JH, Sharif-Naeini R, Dedman A, Patel A, Delmas P, Honoré E. Prog Biophys Mol Biol. 2008 Jun-Jul;97(2-3):180-95. doi: 10.1016/j.pbiomolbio.2008.02.006. Epub 2008 Feb 13. Review.

Contribution of TRPV channels to osmosensory transduction, thirst and vasopressin release. Sharif-Naeini R, Ciura S, Zhang Z, Bourque CW. Kidney Int. 2008 Apr;73(7):811-5. doi: 10.1038/sj.ki.5002788. Epub 2008 Jan 16. Review.

TRP channels and mechanosensory transduction: insights into the arterial myogenic response. Sharif-Naeini R, Dedman A, Folgering JH, Duprat F, Patel A, Nilius B, Honoré E. Pflugers Arch. 2008 Jun;456(3):529-40. doi: 10.1007/s00424-007-0432-y. Epub 2008 Jan 5. Review.

Actin filaments mediate mechanical gating during osmosensory transduction in rat supraoptic nucleus neurons. Zhang Z, Kindrat AN, Sharif-Naeini R, Bourque CW. J Neurosci. 2007 Apr 11;27(15):4008-13.

Neurophysiological characterization of mammalian osmosensitive neurones. Bourque CW, Ciura S, Trudel E, Stachniak TJ, Sharif-Naeini R. Exp Physiol. 2007 May;92(3):499-505. Epub 2007 Mar 9. Review.

An N-terminal variant of Trpv1 channel is required for osmosensory transduction. Sharif Naeini R, Witty MF, Séguéla P, Bourque CW. Nat Neurosci. 2006 Jan;9(1):93-8. Epub 2005 Dec 4.

Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis. Sharif Naeini R, Cahill CM, Ribeiro-da-Silva A, Ménard HA, Henry JL. Eur J Neurosci. 2005 Oct;22(8):2005-15.